Haem.io

The Diagnostic Funnel Expansion

Legacy DiagnosisLung CancerAdenocarcinomaLarge Cell Carcinoma(Reclassified)Squamous CellEGFRALKROS1BRAFKRASMETRETNTRK+ Tier 2 Emerging Biomarkersp40 PositivePD-L1ImmunotherapyEligible
Figure 1: The Fragmentation of Diagnosis.
The "Legacy" diagnosis of Lung Cancer has fractured. Note the dissolution of "Large Cell Carcinoma" (Center), which is now reclassified into specific molecular lineages (Left) or squamous subtypes (Right), mandating complex testing for every patient.
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