Classify AML & MDSin minutes, not hours
Explainable diagnostic intelligence aligned to WHO 2022, ICC 2022 and ELN risk stratification — built for the genomic era.
How Haem.io Works
A simple three-step diagnostic workflow
Extract
Pull key findings from reports into a clean structured profile.
LLM-powered extraction from free-text haematology reports. Identifies mutations, cytogenetics, blast counts, and flow cytometry markers with 100% gene detection accuracy.
Classify
Apply WHO, ICC, and ELN logic to produce a traceable result.
Dual-framework classification against WHO 2022 5th Edition and ICC 2022. Every decision node is traceable with full reasoning chains visible.
Act
Support next-step decisions with diagnosis, risk, and rationale.
Generates ELN 2022 risk for AML, IPSS-M/R for MDS. Provides rationale and evidence for clinical decision support alongside treatment considerations.
See Inside the Platform
From report upload to trial matching — every step is transparent, traceable, and clinician-verifiable.
Upload a report, or enter data manually
Drag and drop a haematology report (morphology, molecular, cytogenetics) and Haem.io's AI extracts every relevant finding — mutations, VAF, cytogenetic abnormalities, blast percentage, and clinical qualifiers. Or enter data manually if you prefer.
- Parses free-text reports from any lab format
- Detects mutations with variant allele frequency
- Identifies cytogenetic abnormalities and karyotype
- Extracts blast counts, flow markers, and clinical context
Review the structured data
Every parsed value is displayed in a structured summary alongside the original report text. Check what the AI extracted, correct anything, and confirm before classification. Nothing is a black box.
- Side-by-side view: parsed data vs original report
- Genetic mutations with classification significance flags
- TP53 allelic status detection (LOH, del17p, multi-hit)
- Cytogenetic complexity and MDS-related abnormalities identified
See the full diagnostic pathway
Haem.io runs the patient data through every decision node in the WHO 2022 and ICC 2022 classification trees. The result isn't just a label — it's the complete execution path showing exactly which rules fired and why.
- Full decision tree visualisation for WHO and ICC
- Every branch point shown: which passed, which failed
- Traceable reasoning — no hidden logic
- Dual classification: WHO 2022 5th Edition + ICC 2022
Dual-framework classification with full reasoning
Haem.io produces both WHO 2022 and ICC 2022 classifications side by side. Each result includes the complete clinical reasoning chain — every rule evaluated, every decision explained. Click "Trace" to see the exact derivation path.
- WHO 2022 5th Edition and ICC 2022 results side by side
- Clinical reasoning steps numbered and explained
- Final pathway derivation from blast percentage to genetic findings
- TP53 multi-hit evaluation with allelic status logic
Risk stratification and clinical decision support
Once classified, Haem.io calculates risk using ELN 2022 (intensive) and ELN 2024 (non-intensive) frameworks. Each risk category includes median survival estimates and the full calculation chain so clinicians can verify every step.
- ELN 2022 intensive and ELN 2024 non-intensive risk
- Median overall survival estimates
- Calculation steps visible and auditable
Automatic clinical trial matching
Based on the classification, genetics, and patient profile, Haem.io automatically identifies eligible clinical trials. Each match includes a confidence score, eligibility status, and what additional data is needed to confirm suitability.
- Matches against curated UK trial database
- Confidence scoring (high, needs data, ineligible)
- Shows what extra information would refine the match
- Direct links to trial registries and contact details
Haem.io Learn
Master WHO 2022 and ICC 2022 haematology classification through guided lessons, real case practice, and daily challenges — built by clinicians, for clinicians.
- Structured AML & MDS classification modules
- Daily practice with real case reports
- ELN risk & IPSS-M stratification training
- Track streaks, earn certificates
Ready to modernise your diagnostic workflow?
Try the interactive AML/MDS classifier — no login required.