Classify leukaemiain minutes, not hours
Explainable diagnostic intelligence aligned to WHO 2022, ICC 2022 and ELN risk stratification — built for the genomic era.
How Haem.io Works
A simple three-step diagnostic workflow
Extract
Pull key findings from reports into a clean structured profile.
LLM-powered extraction from free-text haematology reports. Identifies mutations, cytogenetics, blast counts, and flow cytometry markers with 100% gene detection accuracy.
Classify
Apply WHO, ICC, and ELN logic to produce a traceable result.
Dual-framework classification against WHO 2022 5th Edition and ICC 2022. Every decision node is traceable with full reasoning chains visible.
Act
Support next-step decisions with diagnosis, risk, and rationale.
Generates ELN 2022 and ELN 2024 risk stratification with IPSS-M/R scoring. Provides rationale and evidence for clinical decision support alongside treatment considerations.
See Inside the Platform
From report upload to trial matching — every step is transparent, traceable, and clinician-verifiable.
Upload a report, or enter data manually
Drag and drop a haematology report (morphology, molecular, cytogenetics) and Haem.io's AI extracts every relevant finding — mutations, VAF, cytogenetic abnormalities, blast percentage, and clinical qualifiers. Or enter data manually if you prefer.
- Parses free-text reports from any lab format
- Detects mutations with variant allele frequency
- Identifies cytogenetic abnormalities and karyotype
- Extracts blast counts, flow markers, and clinical context
Review the structured data
Every parsed value is displayed in a structured summary alongside the original report text. Check what the AI extracted, correct anything, and confirm before classification. Nothing is a black box.
- Side-by-side view: parsed data vs original report
- Genetic mutations with classification significance flags
- TP53 allelic status detection (LOH, del17p, multi-hit)
- Cytogenetic complexity and myeloid-related abnormalities identified
See the full diagnostic pathway
Haem.io runs the patient data through every decision node in the WHO 2022 and ICC 2022 classification trees. The result isn't just a label — it's the complete execution path showing exactly which rules fired and why.
- Full decision tree visualisation for WHO and ICC
- Every branch point shown: which passed, which failed
- Traceable reasoning — no hidden logic
- Dual classification: WHO 2022 5th Edition + ICC 2022
Dual-framework classification with full reasoning
Haem.io produces both WHO 2022 and ICC 2022 classifications side by side. Each result includes the complete clinical reasoning chain — every rule evaluated, every decision explained. Click "Trace" to see the exact derivation path.
- WHO 2022 5th Edition and ICC 2022 results side by side
- Clinical reasoning steps numbered and explained
- Final pathway derivation from blast percentage to genetic findings
- TP53 multi-hit evaluation with allelic status logic
Risk stratification and clinical decision support
Once classified, Haem.io calculates risk using ELN 2022 (intensive) and ELN 2024 (non-intensive) frameworks. Each risk category includes median survival estimates and the full calculation chain so clinicians can verify every step.
- ELN 2022 intensive and ELN 2024 non-intensive risk
- Median overall survival estimates
- Calculation steps visible and auditable
Automatic clinical trial matching
Based on the classification, genetics, and patient profile, Haem.io automatically identifies eligible clinical trials. Each match includes a confidence score, eligibility status, and what additional data is needed to confirm suitability.
- Matches against curated UK trial database
- Confidence scoring (high, needs data, ineligible)
- Shows what extra information would refine the match
- Direct links to trial registries and contact details
Endorsed by Leading NHS Clinicians
Senior haematologists across the UK are supporting Haem.io's clinical validation and adoption.
"Haem.io has the potential to transform diagnosis and decision making for patients with haematological malignancies across the NHS."
"Haem.io has the potential to revolutionise the quality of care that patients receive."
"A real step forward in what technology can offer in supporting clinicians to make accurate clinical diagnoses."
"I would wholeheartedly recommend this platform. This will be of significant use for clinicians in the front line."
Haem.io Learn
Master WHO 2022 and ICC 2022 haematology classification through guided lessons, real case practice, and daily challenges — built by clinicians, for clinicians.
- Structured AML & MDS classification modules
- Daily practice with real case reports
- ELN risk & IPSS-M stratification training
- Track streaks, earn certificates
Ready to modernise your diagnostic workflow?
Try the interactive leukaemia classifier — no login required.