Haematology decision support

Clearer criteria review for complex haematology cases.

Haem.io structures case findings and maps them against WHO 2022, ICC 2022 and configured ELN risk criteria, with the inputs and reasoning kept visible for clinician review.

WHO 2022ICC 2022ELN risk logicClinician-in-the-loop
ICC 2022 execution path showing the full criteria decision tree
Workflow

From findings to a reviewable result

A focused three-step criteria review workflow.

01

Structure

Turn case findings into a clinician-reviewable structured profile.

Report findings can be entered manually or structured for review. Mutations, cytogenetics, blast counts, and flow markers remain visible so clinicians can verify the input before criteria are applied.

02

Map

Map the reviewed inputs against configured classification and risk criteria.

The interface presents WHO 2022 and ICC 2022 criteria mapping with the relevant pathway and rationale available for inspection.

03

Review

Support clinician review with classification context, risk logic, and rationale.

Displays risk stratification and supporting rationale where configured. Outputs are decision support for qualified clinicians and do not replace local governance or professional judgement.

Product

A closer look at the platform

From structured findings to classification, risk context and trial review.

01

Upload a report, or enter data manually

Enter structured findings directly, or use a report workflow to prepare key haematology findings for clinician review: mutations, VAF, cytogenetic abnormalities, blast percentage, and clinical qualifiers.

  • Supports structured review of report findings
  • Mutation and variant allele frequency fields
  • Cytogenetic abnormalities and karyotype fields
  • Blast counts, flow markers, and clinical context
Report workflow showing structured findings from a TP53 case report
02

Review the structured data

Parsed or entered values are presented in a structured summary alongside the source material. Clinicians can check and correct the data before criteria are applied.

  • Side-by-side view: parsed data vs original report
  • Genetic mutations with classification significance flags
  • TP53 allelic-status fields, including LOH, del17p and multi-hit
  • Cytogenetic complexity and myeloid-related abnormality review
Data inspector showing parsed mutations (TP53, DNMT3A, TET2, ASXL1), cytogenetics, and original report
03

Inspect the criteria pathway

Reviewed case data is mapped through the relevant WHO 2022 and ICC 2022 criteria. The interface shows the resulting pathway and the rules applied.

  • Criteria pathway visualisation for WHO and ICC
  • Passed and failed branch conditions
  • Reasoning presented alongside the result
  • Dual classification: WHO 2022 5th Edition + ICC 2022
ICC 2022 execution path showing the complete criteria decision tree with highlighted route
04

Compare classification outputs

WHO 2022 and ICC 2022 classification outputs are displayed side by side for clinician review, with the associated reasoning steps.

  • WHO 2022 5th Edition and ICC 2022 results side by side
  • Clinical reasoning steps numbered and explained
  • Pathway from blast percentage to relevant genetic findings
  • TP53 multi-hit evaluation with allelic status logic
Classification results showing WHO 2022 and ICC 2022 with clinical reasoning traces
05

Review configured risk logic

Where configured, Haem.io applies ELN 2022 and ELN 2024 risk logic. The category is shown with its calculation steps and supporting context.

  • ELN 2022 intensive and ELN 2024 non-intensive risk
  • Supporting context for the resulting category
  • Visible calculation steps
Risk stratification showing ELN 2022 Adverse and ELN 2024 Adverse with median survival
06

Clinical trial matching support

Based on classification context, genetics, and case profile, Haem.io can surface potentially relevant clinical trials for review. Each match shows eligibility signals and what additional data is needed to confirm suitability.

  • Searches the available UK trial dataset
  • Eligibility signals for review
  • Shows what extra information would refine the match
  • Direct links to trial registries and contact details
Clinical trial matching showing eligible trials with confidence scores
Clinician feedback

What clinicians have said

Selected feedback shared with Haem.io.

Haem.io has the potential to transform diagnosis and decision making for patients with haematological malignancies across the NHS.

Prof Charles Craddock CBEChair, UK AML Research NetworkUniversity of Warwick

Haem.io has the potential to revolutionise the quality of care that patients receive.

Dr John ChadwickConsultant HaematologistThe Christie NHS Foundation Trust

A real step forward in what technology can offer in supporting clinicians to make accurate clinical diagnoses.

Dr Tom CoatsHaematology ConsultantRoyal Devon & Exeter NHS Trust

I would wholeheartedly recommend this platform. This will be of significant use for clinicians in the front line.

Dr P A CahalinConsultant HaematologistBlackpool Teaching Hospitals NHS Trust

Explore the workflow

The interactive classifier is available to try without creating an account.